Suggested Use: Dissolve 1 sachet into luke warm water (3-4 oz) and stir before consumption. Take on an empty stomach in the morning , before bed or as directed by a health care practitioner. Suitable for children 1 year and older.

Target gb-X is A targeted probiotic blend clinically demonstrated to support mood by influencing the gut-brain axis through the microbiome.† This product can be used safely with other dietary supplements and prescription medications to help support mood.

Target gb-X is powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains, that has been clinically shown to decrease overall cognitive reactivity to:

  • sad mood  
  • rumination   
  • negative thoughts 
  • aggressive thoughts† 

Heightened cognitive reactivity to sad mood is an established risk factor for more serious mood alterations in the otherwise healthy individuals, and is therefore considered an important target for interventions.

Target gb-X Mechanism
  • Powered by Ecologic BARRIER, a 5B CFU blend of 9 probiotic strains

  • Protected by PROBIOACT® Technology for optimal efficacy, stomach acid-stable and shelf-stable without need for refrigeration

  • Hypoallergenic, non-dairy, non-GMO powder in single-serving sachets

Target gb-X with Ecologic BARRIER was specifically designed to influence the gut-brain axis through defined mechanisms including strengthening of the gut barrier function, modulation of cytokines and inflammatory response, production of potentially neuroprotective metabolites, and HPA regulation. Preclinical research emphasized a pronounced shift away from macrophage-produced cytokines to T-lymphocyte-produced cytokines, a reduction in circulating lipopolysaccharide endotoxins, and a marked reduction in transcription of hippocampal genes related to HPA regulation.

Probiotics and the Gut-Brain Axis

The gut-brain axis refers to the bidirectional communication network between the central and autonomic nervous systems and the intestines. Gut-brain communications are mediated by the immune system, endocrine connections such as the hypothalamic-pituitary-adrenal (HPA) axis, and neural pathways involving the enteric nervous system. The gut microbiota is now known to play a pivotal role in gut-brain communications. It is a complex interaction whereas the microbiota engages locally with intestinal cells as well as communicating directly with the central nervous system through neuroendocrine, immune, and metabolic pathways. Research into gut-brain mechanisms is rapidly expanding our understanding and serves to inform the development of targeted probiotic formulations.

Reference: Steenbergen L, Sellaro R, van Hemert S, Bosch JA, Colzato LS. A randomized, controlled trial to test the effect of multispecies probiotics on cognitive reactivity to sad mood. Brain Behav Immun. 2015 Aug;48:258-64.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE

†*All these statements and information on the product descriptions and this website have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program.