Suggested Use: Take 1 scoop daily with or without food, or as directed by your healthcare practitioner. Mix into 16 oz of cold water or liquid of your choice.

MegaMucosa is the first complete mucosal support supplement of its kind, formulated to REBUILD a healthy mucosal barrier.

NOTE:  Recommend to use along with Sanjevani GI Repair for optimum results.

MegaMucosa also contains dairy-free immunoglobulins clinically shown to support a healthy immune response in the mucosa and a state-of-the-art flavobiotic clinically shown to support microbial diversity and alleviate barrier dysfunction, otherwise known as "leaky gut".

The mucosal system is a very important part of the human immune system. Not many people think of mucus as being protective, but it is the main interface between the human body and the outside world. The mucosal system contains 150 times more surface area than skin, which makes it one of the most important immune barriers. The health of the mucosa determines how the body interacts with antigens; therefore, the integrity of the intestinal mucosa can dictate overall immune function.

What does MegaMucosa do?

Immunoglobulins

ImmuoLin is a dairy-free immunoglobulin concentrate that supports healthy digestion, neutralizes environmental toxins, and helps REBUILD protective intestinal barriers. These IgG antibodies can reduce the damage of metabolic endotoxemia ("leaky gut") and neutralize LPS, an endotoxin that triggers mucosal activation. These immune cells can neutralize LPS and other toxins in the intestinal lumen before they reach the intestinal lining.

Amino Acids

There are four key amino acids that play an important role in the production of intestinal mucosa include: L-proline, L-serine, L-cysteine, and L-threonine. These four amino acids have been shown to increase mucin2 production and stimulate mucin synthesis in the colon, resulting in a thicker and healthier mucosal barrier.

Citrus Polyphenols

MicrobiomeX® is a natural citrus extract rich in polyphenols that supports digestive health and immunity by increasing microbial diversity in the gut and maintaining healthy gut barrier function. A clinical study using 500mg of citrus fruit extract found a significant increase in short-chain fatty acid (SCFA) composition, suggesting that these polyphenols may help modulate the microbial composition in the gut.

Research

DLUGOSZ A, ET AL.Increased serum levels of lipopolysaccharide and anti-flagellin antibodies in patients with diarrhea-predominant irritable bowel syndrome. Neurogastroenterol Motil. 2015;27(12):1747-54.

FRITSCHER-RAVENS A, ET AL. Confocal endomicroscopy shows food-associated changes in the intestinal mucosa of patients with irritable bowel syndrome. Gastroenterology. 2014;147(5):1012-20.

ROMIER B, SCHNEIDER YJ, LARONDELLE Y, ET AL.Dietary polyphenols can modulate the intestinal inflammatory response. Nutr Rev. 2009;67(7):363-78.

JASON VS, BURNETT BP.Survival and digestibility of orally-administered immunoglobulin preparations containing IgG through the gastrointestinal tract in humans. Nutrition Journal. 2015;14:22.

FAURE M, METTRAUX C, MOENNOZ D. Specific Amino Acids Increase Mucin Synthesis and Microbiota in Dextran Sulfate Sodium–Treated Rats. J Nutr. 2006;136(6):1558-64.

KÖNIG J, ET AL.Human Intestinal Barrier Function in Health and Disease. Clin Transl Gastroenterol. 2016 Oct 20;7(10):e196. doi: 10.1038/ctg.2016.54.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE

†*All these statements and information on the product descriptions and this website have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program.