Dosing Instructions

Start with ½ scoop daily for one week, then increase to 1 scoop daily with or without food, or as directed by your healthcare practitioner. Mix into 16 oz of cold water or liquid of your choice.

MegaPre™ is the first Precision Prebiotic™ supplement made up of clinically-tested, non-digestible oligosaccharides that can increase microbial diversity and selectively feed beneficial bacteria like Akkermansia muciniphilaFaecalibacterium prausnitzii, and Bifidobacteria. MegaPre™ REINFORCES the beneficial microbial changes created by MegaSporeBiotic™ to promote a strong and diverse microbiome.

 

MegaPre™ contains a proprietary blend of functional fibers that specifically feed these keystone bacteria. This unique blend is made up of clinically-tested-and-published, non-digestible oligosaccharides, derived from non-GMO green and gold kiwi fruit, non-GMO corn cob, and rBST-free cow’s milk

 


Source  Prebiotic Fiber
Non-GMO green and gold kiwifruit  Fructooligosaccharides
Non-GMO corn cob  Xylooligosaccharides
rBST-free cow’s milk  Galactooligosaccharides

 

 

RESEARCH


BLATCHFORD P, STOKLOSINSKI H, EADY S, ET AL.


Consumption of kiwifruit capsules increases Faecalibacterium prausnitzii abundance in functionally constipated individuals: a randomised controlled human trial. J Nutr Sci. 2017; 6: e52.

EVERARD A, LAZAREVIC V, DERRIEN M, ET AL.


Responses of Gut Microbiota and Glucose and Lipid Metabolism to Prebiotics in Genetic Obese and Diet-Induced Leptin-Resistant Mice. Diabetes. 2011 Nov; 60(11): 2775–2786.

YANG J, SUMMANEN PH, HENNING SM, ET AL.


Xylooligosaccharide supplementation alters gut bacteria in both healthy and prediabetic adults: a pilot study. Front Physiol. 2015; 6: 216.

COLLADO MC, DERRIEN M, ISOLAURI E, DE VOS WM, SALMINEN S.


Intestinal integrity and Akkermansia muciniphila, a mucin-degrading member of the intestinal microbiota present in infants, adults, and the elderly. Appl Environ Microbiol. 2007;73: 7767–7770.

DEPEINT F, TZORTZIS G, VULEVIC J, ET AL.


Prebiotic evaluation of a novel galactooligosaccharide mixture produced by the enzymatic activity of Bifidobacterium bifidum NCIMB 41171, in healthy humans: a randomized, double-blind, crossover, placebo-controlled intervention study. Am J Clin Nutr. 2008;87:785-91.

VULEVIC J, JURIC A, TZORTZIS G, AND GIBSON GR.


A Mixture of trans-Galactooligosaccharides Reduces Markers of Metabolic Syndrome and Modulates the Fecal Microbiota and Immune Function of Overweight Adults. J Nutr. 2013;143(3):324-31.

CHELAKKOT C, CHOI Y, KIM DK, ET AL.


Akkermansia muciniphila-derived extracellular vesicles influence gut permeability through the regulation of tight junctions. Experimental & Molecular Medicine. 2018;50:e450.

FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE

†*These statements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, or cure any disease. Always check with your physician before starting a new dietary supplement program.